Tissium is a mission-driven medical device company founded in 2013, headquartered in Paris, with a production facility in Roncq (near Lille) and an office in Boston. We are dedicated to creating a new era of body repair by leveraging our biopolymer platform to develop innovative solutions in surgery for a positive impact on patients' lives.
Tissium’s technology is based on research and intellectual property from the laboratories of Professor Robert Langer (MIT) and Professor Jeffrey M. Karp (Brigham and Women's Hospital), who co-founded the company with Christophe Bancel (CEO) and Maria Pereira (Deputy CEO & Chief Innovation Officer).
We are developing polymers for atraumatic tissue repair in various applications. Today, these polymers are used for sutureless nerve repair, hernia repair, and cardiovascular sealing.
Since our inception, we have raised a total of 170 million euros. Our latest fundraising round, which concluded in April 2023, resulted in 50 million euros in additional funding. This infusion of capital provides us with the necessary resources to finance the commercialization of our first products.
TISSIUM is moving from a phase of GenAI experimentation to a more fundamental transformation: embedding automation and AI into how the company operates. This role owns both the strategy and the execution – identifying where digital creates value, building the solutions, driving adoption, and progressively enabling teams to operate with digital tools. This is a hands-on role for someone who wants to own that mission end to end: the first dedicated hire for it, backed by executive sponsorship.
This is not a backlog execution role - it's an opportunity to define and lead TISSIUM's AI and digital transformation from the ground up. With direct executive sponsorship, a dedicated budget, and the autonomy to identify where AI and digital technologies can create the greatest value across R&D, manufacturing, quality, regulatory, and commercial functions, you'll be expected to ask the right questions, challenge existing ways of working, and translate opportunities into impactful solutions.
This role offers exposure to complex scientific and industrial challenges within a fast-growing MedTech company, placing you at the intersection of every function and giving you the opportunity to shape how a modern medical device company leverages digital technologies. As the organization continues to scale, the role also provides a natural pathway toward leading a broader digital and AI function with increasing strategic influence.
Maintain and evolve existing automations and digital tools – ensure continuity, uptime, and adoption of solutions already in place
Identify and assess opportunities for leveraging digital cross-functionally – proactively engage stakeholders across R&D, Quality, Regulatory, Manufacturing, and Corporate functions to surface high-impact use cases, build business cases, and prioritise by workload vs. value.
Build automations, integrations, and internal tools that remove manual, fragile, orrepetitive work. Develop connectors between data, documents, and systems.
Deliver MVPs (AI-powered tools, workflows, services) used daily by R&D, Quality, Regulatory, and Manufacturing teams. Use GenAI when it helps, deterministic automation when it’s better, and humans where accountability matters.
Drive company-wide GenAI adoption – train and coach teams to use AI tools, embed a technology-first reflex in daily work, and progressively build internal autonomy.
Work directly with scientists and operators in an environment full of unknowns and real constraints – including regulated (GxP) and manufacturing contexts.
Shape the longer-term digital vision – define the roadmap for increased automation, optimisation of digital resources, and advanced initiatives such as programmable polymer behavior simulation.
This posiiton will report to the VP, Portfolio Strategy.
You have proven ability to work directly with non-technical stakeholders – explain, train, and drive adoption.
You Have strong stakeholder management across R&D, Operations, and business teams.
You have a clear, structured communication style; fluent English.
You enjoy ambiguity, ownership, and shipping real things.
You are a hands-on builder — you ship working tools yourself. Comfortable coding in Python (or similar) to build, integrate, and automate; what you can independently ship matters more than deep software-engineering pedigree.
You have experience building automations, APIs, integrations, and MVPs used by real teams.
You are comfortable with cloud environments (AWS or GCP).
You have practical experience with LLMs / GenAI (RAG, fine-tuning, prompt engineering).
We’re looking for a builder who drives change: technical enough to ship real tools yourself, and just as strong at getting people to actually use them.
5–10 years of experience in hands-on engineering, AI, automation, or digital/operational roles
Track record of building and deploying solutions that are actually used by teams , not just POCs.
Has owned the full lifecycle: identifying the opportunity, making the case, building, shipping, and driving adoption.
Comfortable operating as the sole or primary technical person in a non-technical environment.
Experience working directly with senior stakeholders to shape priorities, not just receive them.
Preferred:
Experience in regulated industries (medtech, pharma, biotech) or familiarity with GxP/quality system constraints.
Experience training or coaching non-technical teams on AI/digital tools.
Familiarity with document-heavy workflows (regulatory submissions, quality records clinical operations).
Act with a sense of urgency: Align stakeholders around critical milestones and drive timely execution.
Embrace calculated risk-taking: Take thoughtful risks that create cross-functional impact.
Continuously learn and share: Demonstrate a strong learning mindset, share knowledge, and support team development.
Challenge the status quo: Question existing practices to improve systems, processes, and outcomes.
Balance tactical and strategic thinking: Combine operational excellence with a clear mid-term vision.
Assume positive intent: Foster constructive and respectful collaboration across teams.
Drive active collaboration: Coordinate multiple stakeholders toward shared objectives.
Own outcomes: Take responsibility for project results and deliverables.
Strive for excellence: Lead high-impact improvements in quality and performance.
A dynamic and stimulating environment, with a culture focused on initiative, learning, and continuous improvement.
Real opportunities for growth and development, with evolving career paths and tailored training.
The chance to join an ambitious startup at the forefront of high-impact medical innovation.
A strong commitment to ESG, embedded in our strategy from day one.
Attractive conditions: work-life balance, competitive package, and internal mobility (Paris, Roncq, Boston).
An international and diverse environment, with more than 19 nationalities represented.
HR Interview (30 minutes)
Hiring Manager Interview (1 hour)
Technical Assessment or Case Study
Final On-site Interview ( 2 hours)
In some cases, we may also request professional references (including contact details).
Intrigued? We’d love to hear from you! Apply today - we’re standing by for your resume!
We believe that building an inclusive company starts with a diverse team. We value diversity and encourage applications from people of all backgrounds. We are committed to equal opportunity and do not tolerate discrimination of any kind, including on the basis of gender, gender identity or expression, sexual orientation, origin, family situation, age, beliefs, disability, health status, or any other characteristic protected by law.
Our recruitment process is designed to be simple, transparent, and conversation-driven. We prioritize human interaction and ensure that every application is reviewed carefully and fairly.
